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LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes

Autophagy is an evolutionarily conserved process used for removing surplus and damaged proteins and organelles from the cytoplasm. The unwanted material is incorporated into autophagosomes that eventually fuse with lysosomes, leading to the degradation of their cargo. The fusion event is mediated by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Open
Hauptverfasser: Hubert, Virginie, Peschel, Andrea, Langer, Brigitte, Gröger, Marion, Rees, Andrew, Kain, Renate
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087675/
https://ncbi.nlm.nih.gov/pubmed/27628032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.018648
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