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LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes

Autophagy is an evolutionarily conserved process used for removing surplus and damaged proteins and organelles from the cytoplasm. The unwanted material is incorporated into autophagosomes that eventually fuse with lysosomes, leading to the degradation of their cargo. The fusion event is mediated by...

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Bibliografische gegevens
Gepubliceerd in:Biol Open
Hoofdauteurs: Hubert, Virginie, Peschel, Andrea, Langer, Brigitte, Gröger, Marion, Rees, Andrew, Kain, Renate
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087675/
https://ncbi.nlm.nih.gov/pubmed/27628032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.018648
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