Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila

During autophagy, phagophores capture portions of cytoplasm and form double-membrane autophagosomes to deliver cargo for lysosomal degradation. How autophagosomes gain competence to fuse with late endosomes and lysosomes is not known. In this paper, we show that Syntaxin17 is recruited to the outer...

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Bibliographic Details
Main Authors: Takáts, Szabolcs, Nagy, Péter, Varga, Ágnes, Pircs, Karolina, Kárpáti, Manuéla, Varga, Kata, Kovács, Attila L., Hegedűs, Krisztina, Juhász, Gábor
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653357/
https://ncbi.nlm.nih.gov/pubmed/23671310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201211160
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