Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila

Phagophore-derived autophagosomes deliver cytoplasmic material to lysosomes for degradation and reuse. Autophagy mediated by the incompletely characterized actions of Atg proteins is involved in numerous physiological and pathological settings including stress resistance, immunity, aging, cancer, an...

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Hlavní autoři: Nagy, Péter, Kárpáti, Manuéla, Varga, Ágnes, Pircs, Karolina, Venkei, Zsolt, Takáts, Szabolcs, Varga, Kata, Érdi, Balázs, Hegedűs, Krisztina, Juhász, Gábor
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
Basic Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077884/
https://ncbi.nlm.nih.gov/pubmed/24419107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27442
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