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LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes

Autophagy is an evolutionarily conserved process used for removing surplus and damaged proteins and organelles from the cytoplasm. The unwanted material is incorporated into autophagosomes that eventually fuse with lysosomes, leading to the degradation of their cargo. The fusion event is mediated by...

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Detalles Bibliográficos
Publicado en:Biol Open
Main Authors: Hubert, Virginie, Peschel, Andrea, Langer, Brigitte, Gröger, Marion, Rees, Andrew, Kain, Renate
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087675/
https://ncbi.nlm.nih.gov/pubmed/27628032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.018648
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