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Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17

Macroautophagy is an evolutionarily conserved catabolic mechanism that delivers intracellular constituents to lysosomes using autophagosomes. To achieve degradation, lysosomes must fuse with closed autophagosomes. We previously reported that the soluble N-ethylmaleimide–sensitive factor attachment p...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Matsui, Takahide, Jiang, Peidu, Nakano, Saori, Sakamaki, Yuriko, Yamamoto, Hayashi, Mizushima, Noboru
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080929/
https://ncbi.nlm.nih.gov/pubmed/29789439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201712058
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