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Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17

Macroautophagy is an evolutionarily conserved catabolic mechanism that delivers intracellular constituents to lysosomes using autophagosomes. To achieve degradation, lysosomes must fuse with closed autophagosomes. We previously reported that the soluble N-ethylmaleimide–sensitive factor attachment p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biol
Prif Awduron: Matsui, Takahide, Jiang, Peidu, Nakano, Saori, Sakamaki, Yuriko, Yamamoto, Hayashi, Mizushima, Noboru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Rockefeller University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080929/
https://ncbi.nlm.nih.gov/pubmed/29789439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201712058
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