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Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17

Macroautophagy is an evolutionarily conserved catabolic mechanism that delivers intracellular constituents to lysosomes using autophagosomes. To achieve degradation, lysosomes must fuse with closed autophagosomes. We previously reported that the soluble N-ethylmaleimide–sensitive factor attachment p...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: Matsui, Takahide, Jiang, Peidu, Nakano, Saori, Sakamaki, Yuriko, Yamamoto, Hayashi, Mizushima, Noboru
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080929/
https://ncbi.nlm.nih.gov/pubmed/29789439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201712058
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