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LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes

Autophagy is an evolutionarily conserved process used for removing surplus and damaged proteins and organelles from the cytoplasm. The unwanted material is incorporated into autophagosomes that eventually fuse with lysosomes, leading to the degradation of their cargo. The fusion event is mediated by...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Hubert, Virginie, Peschel, Andrea, Langer, Brigitte, Gröger, Marion, Rees, Andrew, Kain, Renate
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087675/
https://ncbi.nlm.nih.gov/pubmed/27628032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.018648
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