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LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes

Autophagy is an evolutionarily conserved process used for removing surplus and damaged proteins and organelles from the cytoplasm. The unwanted material is incorporated into autophagosomes that eventually fuse with lysosomes, leading to the degradation of their cargo. The fusion event is mediated by...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Biol Open
Κύριοι συγγραφείς: Hubert, Virginie, Peschel, Andrea, Langer, Brigitte, Gröger, Marion, Rees, Andrew, Kain, Renate
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Company of Biologists Ltd 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087675/
https://ncbi.nlm.nih.gov/pubmed/27628032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.018648
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