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LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes
Autophagy is an evolutionarily conserved process used for removing surplus and damaged proteins and organelles from the cytoplasm. The unwanted material is incorporated into autophagosomes that eventually fuse with lysosomes, leading to the degradation of their cargo. The fusion event is mediated by...
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| Publié dans: | Biol Open |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5087675/ https://ncbi.nlm.nih.gov/pubmed/27628032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.018648 |
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