Crystal Structure of SgcJ, An NTF2-Like Superfamily Protein Involved in Biosynthesis of the 9-Membered Enediyne Antitumor Antibiotic C-1027

Comparative analysis of the enediyne biosynthetic gene clusters revealed sets of conserved genes serving as outstanding candidates for the enediyne core. Here we report the crystal structures of SgcJ and its homologue NCS-Orf16, together with gene inactivation and site-directed mutagenesis studies,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Antibiot (Tokyo)
Main Authors: Huang, Tingting, Chang, Chin-Yuan, Lohman, Jeremy R., Rudolf, Jeffrey D., Kim, Youngchang, Chang, Changsoo, Yang, Dong, Ma, Ming, Yan, Xiaohui, Crnovcic, Ivana, Bigelow, Lance, Clancy, Shonda, Bingman, Craig A., Yennamalli, Ragothaman M., Babnigg, Gyorgy, Joachimiak, Andrzej, Phillips, George N., Shen, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083130/
https://ncbi.nlm.nih.gov/pubmed/27406907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2016.88
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados