Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade

Immune checkpoint blockade represents a major breakthrough in cancer therapy, however responses are not universal. Genomic and immune features in pre-treatment tumor biopsies have been reported to correlate with response in patients with melanoma and other cancers, but robust biomarkers have not bee...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Chen, Pei-Ling, Roh, Whijae, Reuben, Alexandre, Cooper, Zachary A., Spencer, Christine N., Prieto, Peter A., Miller, John P., Bassett, Roland L., Gopalakrishnan, Vancheswaran, Wani, Khalida, De Macedo, Mariana Petaccia, Austin-Breneman, Jacob L., Jiang, Hong, Chang, Qing, Reddy, Sangeetha M., Chen, Wei-Shen, Tetzlaff, Michael T., Broaddus, Russell J., Davies, Michael A., Gershenwald, Jeffrey E., Haydu, Lauren, Lazar, Alexander J., Patel, Sapna P., Hwu, Patrick, Hwu, Wen-Jen, Diab, Adi, Glitza, Isabella C., Woodman, Scott E., Vence, Luis M., Wistuba, Ignacio I., Amaria, Rodabe N., Kwong, Lawrence N., Prieto, Victor, Davis, R. Eric, Ma, Wencai, Overwijk, Willem W., Sharpe, Arlene H., Hu, Jianhua, Futreal, P. Andrew, Blando, Jorge, Sharma, Padmanee, Allison, James P., Chin, Lynda, Wargo, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082984/
https://ncbi.nlm.nih.gov/pubmed/27301722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-1545
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados