Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade

Immune checkpoint blockade represents a major breakthrough in cancer therapy, however responses are not universal. Genomic and immune features in pre-treatment tumor biopsies have been reported to correlate with response in patients with melanoma and other cancers, but robust biomarkers have not bee...

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Xehetasun bibliografikoak
Argitaratua izan da:Cancer Discov
Egile Nagusiak: Chen, Pei-Ling, Roh, Whijae, Reuben, Alexandre, Cooper, Zachary A., Spencer, Christine N., Prieto, Peter A., Miller, John P., Bassett, Roland L., Gopalakrishnan, Vancheswaran, Wani, Khalida, De Macedo, Mariana Petaccia, Austin-Breneman, Jacob L., Jiang, Hong, Chang, Qing, Reddy, Sangeetha M., Chen, Wei-Shen, Tetzlaff, Michael T., Broaddus, Russell J., Davies, Michael A., Gershenwald, Jeffrey E., Haydu, Lauren, Lazar, Alexander J., Patel, Sapna P., Hwu, Patrick, Hwu, Wen-Jen, Diab, Adi, Glitza, Isabella C., Woodman, Scott E., Vence, Luis M., Wistuba, Ignacio I., Amaria, Rodabe N., Kwong, Lawrence N., Prieto, Victor, Davis, R. Eric, Ma, Wencai, Overwijk, Willem W., Sharpe, Arlene H., Hu, Jianhua, Futreal, P. Andrew, Blando, Jorge, Sharma, Padmanee, Allison, James P., Chin, Lynda, Wargo, Jennifer A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082984/
https://ncbi.nlm.nih.gov/pubmed/27301722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-15-1545
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