Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma

We have made major advances in the treatment of melanoma through the use of targeted therapy and immune checkpoint blockade; however, clinicians are posed with therapeutic dilemmas regarding timing and sequence of therapy. There is a growing appreciation of the impact of antitumor immune responses t...

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Vydáno v:Oncoimmunology
Hlavní autoři: Cooper, Zachary A., Reuben, Alexandre, Spencer, Christine N., Prieto, Peter A., Austin-Breneman, Jacob L., Jiang, Hong, Haymaker, Cara, Gopalakrishnan, Vancheswaran, Tetzlaff, Michael T., Frederick, Dennie T., Sullivan, Ryan J., Amaria, Rodabe N., Patel, Sapna P., Hwu, Patrick, Woodman, Scott E., Glitza, Isabella C., Diab, Adi, Vence, Luis M., Rodriguez-Canales, Jaime, Parra, Edwin R., Wistuba, Ignacio I., Coussens, Lisa M., Sharpe, Arlene H., Flaherty, Keith T., Gershenwald, Jeffrey E., Chin, Lynda, Davies, Michael A., Clise-Dwyer, Karen, Allison, James P., Sharma, Padmanee, Wargo, Jennifer A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839346/
https://ncbi.nlm.nih.gov/pubmed/27141370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1136044
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