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Toxic PR poly-dipeptides encoded by the C9orf72 repeat expansion target LC domain polymers
Two complementary approaches were used in search of the intracellular targets of the toxic PR poly-dipeptide encoded by the repeat sequences expanded in the C9orf72 form of amyotrophic lateral sclerosis. The top categories of PR(n)-bound proteins include constituents of non-membrane invested cellula...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5076566/ https://ncbi.nlm.nih.gov/pubmed/27768897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.10.003 |
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