The LC Domain of hnRNPA2 Adopts Similar Conformations in Hydrogel Polymers, Liquid-like Droplets and Nuclei

Many DNA and RNA regulatory proteins contain polypeptide domains that are unstructured when analyzed in cell lysates. These domains are typified by an over-representation of a limited number of amino acids and have been termed prion-like, intrinsically disordered or low complexity (LC) domains. When...

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Vydáno v:Cell
Hlavní autoři: Xiang, Siheng, Kato, Masato, Wu, Leeju, Lin, Yi, Ding, Ming, Zhang, Yajie, Yu, Yonghao, McKnight, Steven L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879888/
https://ncbi.nlm.nih.gov/pubmed/26544936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.040
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