Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model

Genetic ablation or pharmacologic inhibition of matrix metalloproteinase-8 (MMP8) improves survival in an adult murine sepsis model. Because developmental age influences the host inflammatory response, we hypothesized that developmental age influences the role of MMP8 in sepsis. First, we compared s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Med
Päätekijät: Atkinson, Sarah J, Varisco, Brian M, Sandquist, Mary, Daly, Meghan N, Klingbeil, Lindsey, Kuethe, Joshua W, Midura, Emily F, Harmon, Kelli, Opoka, Amy, Lahni, Patrick, Piraino, Giovanna, Hake, Paul, Zingarelli, Basilia, Mortensen, Joel E, Wynn, James L, Wong, Hector R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Feinstein Institute for Medical Research 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072408/
https://ncbi.nlm.nih.gov/pubmed/27506554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00058
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia