Role of matrix metalloproteinase-8 as a mediator of injury in intestinal ischemia and reperfusion

Acute mesenteric ischemia is associated with high morbidity and mortality. In recent studies, we found that the intestine is an important source of matrix metalloproteinase (MMP)8 during intestinal injury. We hypothesized that genetic ablation or pharmacological inhibition of MMP8 would reduce intes...

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Veröffentlicht in:FASEB J
Hauptverfasser: Daly, Meghan C., Atkinson, Sarah J., Varisco, Brian M., Klingbeil, Lindsey, Hake, Paul, Lahni, Patrick, Piraino, Giovanna, Wu, David, Hogan, Simon P., Zingarelli, Basilia, Wong, Hector R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5024695/
https://ncbi.nlm.nih.gov/pubmed/27435263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600242R
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