THE AMPK ACTIVATOR AICAR AMELIORATES AGE-DEPENDENT MYOCARDIAL INJURY IN MURINE HEMORRHAGIC SHOCK

The development of myocardial dysfunction in patients with hemorrhagic shock is significantly impacted by the patient age. AMP-activated protein kinase (AMPK) is a pivotal orchestrator of energy homeostasis, which coordinates metabolic recovery after cellular stress. We investigated whether AMPK-reg...

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Bibliografski detalji
Izdano u:Shock
Glavni autori: Matsiukevich, Dzmitry, Piraino, Giovanna, Klingbeil, Lindsey R., Hake, Paul W., Wolfe, Vivian, O’Connor, Michael, Zingarelli, Basilia
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5167668/
https://ncbi.nlm.nih.gov/pubmed/27513082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000730
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