Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model

Genetic ablation or pharmacologic inhibition of matrix metalloproteinase-8 (MMP8) improves survival in an adult murine sepsis model. Because developmental age influences the host inflammatory response, we hypothesized that developmental age influences the role of MMP8 in sepsis. First, we compared s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Med
मुख्य लेखकों: Atkinson, Sarah J, Varisco, Brian M, Sandquist, Mary, Daly, Meghan N, Klingbeil, Lindsey, Kuethe, Joshua W, Midura, Emily F, Harmon, Kelli, Opoka, Amy, Lahni, Patrick, Piraino, Giovanna, Hake, Paul, Zingarelli, Basilia, Mortensen, Joel E, Wynn, James L, Wong, Hector R
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Feinstein Institute for Medical Research 2016
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072408/
https://ncbi.nlm.nih.gov/pubmed/27506554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00058
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