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Sedative-Hypnotic Binding to 11β-Hydroxylase

BACKGROUND: Etomidate potently suppresses adrenocortical steroid synthesis with potentially deleterious consequences by binding to 11β-hydroxylase and inhibiting its function. The authors hypothesized that other sedative-hypnotics currently in clinical use or under development (or their metabolites)...

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Pubblicato in:Anesthesiology
Autori principali: Pejo, Ervin, Zhou, Xiaojuan, Husain, S. Shaukat, Raines, Douglas E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069162/
https://ncbi.nlm.nih.gov/pubmed/27541316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001304
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