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Comprehensive characterization of ligand‐induced plasticity changes in a dimeric enzyme

An enzyme's inherent structural plasticity is frequently associated with substrate binding, yet detailed structural characterization of flexible proteins remains challenging. This study employs complementary biophysical methods to characterize the partially unfolded structure of substrate‐free...

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Pubblicato in:FEBS J
Autori principali: Baettig, Oliver M., Shi, Kun, Yachnin, Brahm J., Burk, David L., Berghuis, Albert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053276/
https://ncbi.nlm.nih.gov/pubmed/27333541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13788
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