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Comprehensive characterization of ligand‐induced plasticity changes in a dimeric enzyme

An enzyme's inherent structural plasticity is frequently associated with substrate binding, yet detailed structural characterization of flexible proteins remains challenging. This study employs complementary biophysical methods to characterize the partially unfolded structure of substrate‐free...

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Detalhes bibliográficos
Publicado no:FEBS J
Principais autores: Baettig, Oliver M., Shi, Kun, Yachnin, Brahm J., Burk, David L., Berghuis, Albert M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053276/
https://ncbi.nlm.nih.gov/pubmed/27333541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13788
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