An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation

Neutrophilic differentiation is dependent on CCAAT enhancer-binding protein α (C/EBPα), a transcription factor expressed in multiple organs including the bone marrow. Using functional genomic technologies in combination with clustered regularly-interspaced short palindromic repeat (CRISPR)/CRISPR-as...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Avellino, Roberto, Havermans, Marije, Erpelinck, Claudia, Sanders, Mathijs A., Hoogenboezem, Remco, van de Werken, Harmen J. G., Rombouts, Elwin, van Lom, Kirsten, van Strien, Paulina M. H., Gebhard, Claudia, Rehli, Michael, Pimanda, John, Beck, Dominik, Erkeland, Stefan, Kuiken, Thijs, de Looper, Hans, Gröschel, Stefan, Touw, Ivo, Bindels, Eric, Delwel, Ruud
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2016
Aiheet:
Hematopoiesis and Stem Cells
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043424/
https://ncbi.nlm.nih.gov/pubmed/26966090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-01-695759
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