Novel proteasome inhibitor ixazomib sensitizes neuroblastoma cells to doxorubicin treatment

Neuroblastoma (NB) is the most common extracranial malignant solid tumor seen in children and continues to lead to the death of many pediatric cancer patients. The poor outcome in high risk NB is largely attributed to the development of chemoresistant tumor cells. Doxorubicin (dox) has been widely e...

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Udgivet i:Sci Rep
Main Authors: Li, Haoyu, Chen, Zhenghu, Hu, Ting, Wang, Long, Yu, Yang, Zhao, Yanling, Sun, Wenijing, Guan, Shan, Pang, Jonathan C., Woodfield, Sarah E., Liu, Qing, Yang, Jianhua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043366/
https://ncbi.nlm.nih.gov/pubmed/27687684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34397
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