TAK1 inhibitor 5Z-7-oxozeaenol sensitizes cervical cancer to doxorubicin-induced apoptosis

Aberrant activation of nuclear factor-κB (NF-κB) allows cancer cells to escape chemotherapy-induced cell death and acts as one of the major mechanisms of acquired chemoresistance in cervical cancer. TAK1, a crucial mediator that upregulates NF-κB activation in response to cellular genotoxic stress,...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Guan, Shan, Lu, Jiaxiong, Zhao, Yanling, Woodfield, Sarah E., Zhang, Huiyuan, Xu, Xin, Yu, Yang, Zhao, Jing, Bieerkehazhi, Shayahati, Liang, Haoqian, Yang, Jianhua, Zhang, Fuchun, Sun, Surong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464900/
https://ncbi.nlm.nih.gov/pubmed/28430599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16895
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky