TAK1 inhibitor 5Z-7-oxozeaenol sensitizes cervical cancer to doxorubicin-induced apoptosis

Aberrant activation of nuclear factor-κB (NF-κB) allows cancer cells to escape chemotherapy-induced cell death and acts as one of the major mechanisms of acquired chemoresistance in cervical cancer. TAK1, a crucial mediator that upregulates NF-κB activation in response to cellular genotoxic stress,...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Guan, Shan, Lu, Jiaxiong, Zhao, Yanling, Woodfield, Sarah E., Zhang, Huiyuan, Xu, Xin, Yu, Yang, Zhao, Jing, Bieerkehazhi, Shayahati, Liang, Haoqian, Yang, Jianhua, Zhang, Fuchun, Sun, Surong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464900/
https://ncbi.nlm.nih.gov/pubmed/28430599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16895
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