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TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy
Treatment failure in high risk neuroblastoma is largely due to development of chemoresistance. NF-κB activation is one of the resistance mechanisms for cancer cells to escape from chemotherapy-induced cell-death. TAK1 is an essential component in genotoxic stresses-induced NF-κB activation; however,...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778057/ https://ncbi.nlm.nih.gov/pubmed/23700229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0864-0 |
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