TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy

Treatment failure in high risk neuroblastoma is largely due to development of chemoresistance. NF-κB activation is one of the resistance mechanisms for cancer cells to escape from chemotherapy-induced cell-death. TAK1 is an essential component in genotoxic stresses-induced NF-κB activation; however,...

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Hlavní autoři: Fan, Yihui, Cheng, Jin, Vasudevan, Sanjeev A., Patel, Roma H., Liang, Li, Xu, Xin, Zhao, Yanling, Jia, Wei, Lu, Fengmin, Zhang, Hong, Nuchtern, Jed G., Kim, Eugene S., Jianhua, Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778057/
https://ncbi.nlm.nih.gov/pubmed/23700229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0864-0
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