Novel proteasome inhibitor delanzomib sensitizes cervical cancer cells to doxorubicin-induced apoptosis via stabilizing tumor suppressor proteins in the p53 pathway

Cervical cancer, the third most commonly occurring cancer, is the second leading cause of cancer related mortality among women. Aberrant ubiquitination and proteasome activity, both human papillomavirus and tumor derived, have been shown to contribute to tumor angiogenesis, proliferation, and invasi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Guo, Kevin Y., Han, Lili, Li, Xinyu, Yang, Andrew V., Lu, Jiaxiong, Guan, Shan, Li, Hui, Yu, Yang, Zhao, Yanling, Yang, Jianhua, Zhang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768391/
https://ncbi.nlm.nih.gov/pubmed/29371974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23166
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