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Novel proteasome inhibitor delanzomib sensitizes cervical cancer cells to doxorubicin-induced apoptosis via stabilizing tumor suppressor proteins in the p53 pathway

Cervical cancer, the third most commonly occurring cancer, is the second leading cause of cancer related mortality among women. Aberrant ubiquitination and proteasome activity, both human papillomavirus and tumor derived, have been shown to contribute to tumor angiogenesis, proliferation, and invasi...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Guo, Kevin Y., Han, Lili, Li, Xinyu, Yang, Andrew V., Lu, Jiaxiong, Guan, Shan, Li, Hui, Yu, Yang, Zhao, Yanling, Yang, Jianhua, Zhang, Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768391/
https://ncbi.nlm.nih.gov/pubmed/29371974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23166
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