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Novel proteasome inhibitor delanzomib sensitizes cervical cancer cells to doxorubicin-induced apoptosis via stabilizing tumor suppressor proteins in the p53 pathway

Cervical cancer, the third most commonly occurring cancer, is the second leading cause of cancer related mortality among women. Aberrant ubiquitination and proteasome activity, both human papillomavirus and tumor derived, have been shown to contribute to tumor angiogenesis, proliferation, and invasi...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Oncotarget
Κύριοι συγγραφείς: Guo, Kevin Y., Han, Lili, Li, Xinyu, Yang, Andrew V., Lu, Jiaxiong, Guan, Shan, Li, Hui, Yu, Yang, Zhao, Yanling, Yang, Jianhua, Zhang, Hong
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768391/
https://ncbi.nlm.nih.gov/pubmed/29371974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23166
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