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Novel proteasome inhibitor ixazomib sensitizes neuroblastoma cells to doxorubicin treatment

Neuroblastoma (NB) is the most common extracranial malignant solid tumor seen in children and continues to lead to the death of many pediatric cancer patients. The poor outcome in high risk NB is largely attributed to the development of chemoresistant tumor cells. Doxorubicin (dox) has been widely e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Haoyu, Chen, Zhenghu, Hu, Ting, Wang, Long, Yu, Yang, Zhao, Yanling, Sun, Wenijing, Guan, Shan, Pang, Jonathan C., Woodfield, Sarah E., Liu, Qing, Yang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043366/
https://ncbi.nlm.nih.gov/pubmed/27687684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34397
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