Novel multiple tyrosine kinase inhibitor ponatinib inhibits bFGF-activated signaling in neuroblastoma cells and suppresses neuroblastoma growth in vivo

Neuroblastoma (NB) is one of the most common pediatric malignancies in children. Abnormal activation of receptor tyrosine kinases contributes to the pathological development of NB. Therefore, targeting tyrosine kinase receptors to cure NB is a promising strategy. Here, we report that a multi-targete...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Haoyu, Wang, Yongfeng, Chen, Zhenghu, Lu, Jiaxiong, Pan, Jessie, Yu, Yang, Zhao, Yanling, Zhang, Huiyuan, Hu, Ting, Liu, Qing, Yang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351597/
https://ncbi.nlm.nih.gov/pubmed/27564113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11580
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