Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis

Neuroblastoma (NB), which accounts for about 15% of cancer-related mortality in children, is the most common extracranial malignant neoplasm in children. Elevated level of proteasome activity promotes cancer development and the inhibition of proteasome activity is a promising strategy for cancer tre...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Guan, Shan, Zhao, Yanling, Lu, Jiaxiong, Yu, Yang, Sun, Wenjing, Mao, Xinfang, Chen, Zhenghu, Xu, Xin, Pan, Jessie, Sun, Surong, Yang, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342787/
https://ncbi.nlm.nih.gov/pubmed/27713150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12427
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