Novel Src/Abl tyrosine kinase inhibitor bosutinib suppresses neuroblastoma growth via inhibiting Src/Abl signaling

Neuroblastoma (NB) is the most common extracranial solid tumor in children. Aberrant activation of the non-receptor tyrosine kinases Src and c-Abl contributes to the progression of NB. Thus, targeting these kinases could be a promising strategy for NB therapy. In this paper, we report that the poten...

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Vydáno v:Oncotarget
Hlavní autoři: Bieerkehazhi, Shayahati, Chen, Zhenghu, Zhao, Yanling, Yu, Yang, Zhang, Huiyuan, Vasudevan, Sanjeev A., Woodfield, Sarah E., Tao, Ling, Yi, Joanna S., Muscal, Jodi A., Pang, Jonathan C., Guan, Shan, Zhang, Hong, Nuchtern, Jed G., Li, Hui, Li, Huiwu, Yang, Jianhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352070/
https://ncbi.nlm.nih.gov/pubmed/27903968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13643
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