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Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication
Prions are the infectious agents causing transmissible spongiform encephalopathies (TSE), progressive, inexorably lethal neurological diseases. Antibodies targeting the globular domain (GD) of the cellular prion protein PrP(C) trigger a neurotoxic syndrome morphologically and molecularly similar to...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5042507/ https://ncbi.nlm.nih.gov/pubmed/27684562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163601 |
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