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The biological function of the cellular prion protein: an update
The misfolding of the cellular prion protein (PrP(C)) causes fatal neurodegenerative diseases. Yet PrP(C) is highly conserved in mammals, suggesting that it exerts beneficial functions preventing its evolutionary elimination. Ablation of PrP(C) in mice results in well-defined structural and function...
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| Publicado no: | BMC Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5412054/ https://ncbi.nlm.nih.gov/pubmed/28464931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-017-0375-5 |
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