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Physiological Functions of the Cellular Prion Protein

The prion protein, PrP(C), is a small, cell-surface glycoprotein notable primarily for its critical role in pathogenesis of the neurodegenerative disorders known as prion diseases. A hallmark of prion diseases is the conversion of PrP(C) into an abnormally folded isoform, which provides a template f...

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Pubblicato in:Front Mol Biosci
Autori principali: Castle, Andrew R., Gill, Andrew C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382174/
https://ncbi.nlm.nih.gov/pubmed/28428956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2017.00019
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