Neurotoxic Antibodies against the Prion Protein Do Not Trigger Prion Replication

Prions are the infectious agents causing transmissible spongiform encephalopathies (TSE), progressive, inexorably lethal neurological diseases. Antibodies targeting the globular domain (GD) of the cellular prion protein PrP(C) trigger a neurotoxic syndrome morphologically and molecularly similar to...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Frontzek, Karl, Pfammatter, Manuela, Sorce, Silvia, Senatore, Assunta, Schwarz, Petra, Moos, Rita, Frauenknecht, Katrin, Hornemann, Simone, Aguzzi, Adriano
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042507/
https://ncbi.nlm.nih.gov/pubmed/27684562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163601
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