Llwytho...
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
α-synuclein (α-syn) is a 140-residue intrinsically disordered protein that is involved in neuronal and synaptic vesicle plasticity but its aggregation to form amyloid fibrils is the hallmark of Parkinson’s disease (PD). The interaction between α-syn and lipid surfaces is believed to be a key feature...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Chem Biol |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2015
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5019199/ https://ncbi.nlm.nih.gov/pubmed/25643172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1750 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|