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Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
Intracellular α-synuclein deposits, known as Lewy bodies, have been linked to a range of neurodegenerative disorders, including Parkinson’s disease. α-Synuclein binds to synthetic and biological lipids, and this interaction has been shown to play a crucial role for both α-synuclein’s native function...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932957/ https://ncbi.nlm.nih.gov/pubmed/27298346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601899113 |
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