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Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
Intracellular α-synuclein deposits, known as Lewy bodies, have been linked to a range of neurodegenerative disorders, including Parkinson’s disease. α-Synuclein binds to synthetic and biological lipids, and this interaction has been shown to play a crucial role for both α-synuclein’s native function...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932957/ https://ncbi.nlm.nih.gov/pubmed/27298346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601899113 |
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