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Beta‐amyloid 1‐42 monomers, but not oligomers, produce PHF‐like conformation of Tau protein
The mechanistic relationship between amyloid β1‐42 (Aβ1‐42) and the alteration of Tau protein are debated. We investigated the effect of Aβ1‐42 monomers and oligomers on Tau, using mice expressing wild‐type human Tau that do not spontaneously develop Tau pathology. After intraventricular injection o...
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| Yayımlandı: | Aging Cell |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013016/ https://ncbi.nlm.nih.gov/pubmed/27406053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12500 |
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