Beta‐amyloid 1‐42 monomers, but not oligomers, produce PHF‐like conformation of Tau protein

The mechanistic relationship between amyloid β1‐42 (Aβ1‐42) and the alteration of Tau protein are debated. We investigated the effect of Aβ1‐42 monomers and oligomers on Tau, using mice expressing wild‐type human Tau that do not spontaneously develop Tau pathology. After intraventricular injection o...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Aging Cell
Hlavní autoři: Manassero, Giusi, Guglielmotto, Michela, Zamfir, Raluca, Borghi, Roberta, Colombo, Laura, Salmona, Mario, Perry, George, Odetti, Patrizio, Arancio, Ottavio, Tamagno, Elena, Tabaton, Massimo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013016/
https://ncbi.nlm.nih.gov/pubmed/27406053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12500
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky