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Beta‐amyloid 1‐42 monomers, but not oligomers, produce PHF‐like conformation of Tau protein

The mechanistic relationship between amyloid β1‐42 (Aβ1‐42) and the alteration of Tau protein are debated. We investigated the effect of Aβ1‐42 monomers and oligomers on Tau, using mice expressing wild‐type human Tau that do not spontaneously develop Tau pathology. After intraventricular injection o...

詳細記述

保存先:
書誌詳細
出版年:Aging Cell
主要な著者: Manassero, Giusi, Guglielmotto, Michela, Zamfir, Raluca, Borghi, Roberta, Colombo, Laura, Salmona, Mario, Perry, George, Odetti, Patrizio, Arancio, Ottavio, Tamagno, Elena, Tabaton, Massimo
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013016/
https://ncbi.nlm.nih.gov/pubmed/27406053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12500
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