Oxidative Stress Mediates the Pathogenic Effect of Different Alzheimer's Disease Risk Factors

Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting the elderly population. Mechanistically, the major cause of the disease bases on the altered processing of the amyloid-β (Aβ) precursor protein (APP), resulting in the accumulation and aggregation of neurotoxic forms...

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Bibliographic Details
Main Authors: Guglielmotto, Michela, Giliberto, Luca, Tamagno, Elena, Tabaton, Massimo
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2010
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874401/
https://ncbi.nlm.nih.gov/pubmed/20552043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/neuro.24.003.2010
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