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The Unexpected Role of Aβ(1-42) Monomers in the Pathogenesis of Alzheimer’s Disease
Amyloid-β (Aβ) has been proposed as a biomarker and a drug target for the therapy of Alzheimer’s disease (AD). The neurotoxic entity and relevance of each conformational form of Aβ to AD pathology is still under debate; Aβ oligomers are considered the major killer form of the peptide whereas monomer...
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| Publicado no: | J Alzheimers Dis |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
IOS Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5870015/ https://ncbi.nlm.nih.gov/pubmed/29103036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170581 |
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