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Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C(4) to leukotriene D(4)

Leukotrienes (LTs) play major roles in lung immune responses, and LTD(4) is the most potent agonist for cysteinyl LT1, leading to bronchoconstriction and tissue remodeling. Here, we studied LT crosstalk between myeloid cells and pulmonary epithelial cells. Monocytic cells (Mono Mac 6 cell line, prim...

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Dades bibliogràfiques
Publicat a:J Lipid Res
Autors principals: Lukic, Ana, Ji, Jie, Idborg, Helena, Samuelsson, Bengt, Palmberg, Lena, Gabrielsson, Susanne, Rådmark, Olof
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003151/
https://ncbi.nlm.nih.gov/pubmed/27436590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066910
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