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Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C(4) to leukotriene D(4)
Leukotrienes (LTs) play major roles in lung immune responses, and LTD(4) is the most potent agonist for cysteinyl LT1, leading to bronchoconstriction and tissue remodeling. Here, we studied LT crosstalk between myeloid cells and pulmonary epithelial cells. Monocytic cells (Mono Mac 6 cell line, prim...
Gespeichert in:
| Veröffentlicht in: | J Lipid Res |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Biochemistry and Molecular Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5003151/ https://ncbi.nlm.nih.gov/pubmed/27436590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066910 |
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