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Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C(4) to leukotriene D(4)
Leukotrienes (LTs) play major roles in lung immune responses, and LTD(4) is the most potent agonist for cysteinyl LT1, leading to bronchoconstriction and tissue remodeling. Here, we studied LT crosstalk between myeloid cells and pulmonary epithelial cells. Monocytic cells (Mono Mac 6 cell line, prim...
Enregistré dans:
| Publié dans: | J Lipid Res |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Biochemistry and Molecular Biology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5003151/ https://ncbi.nlm.nih.gov/pubmed/27436590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066910 |
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