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Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C(4) to leukotriene D(4)

Leukotrienes (LTs) play major roles in lung immune responses, and LTD(4) is the most potent agonist for cysteinyl LT1, leading to bronchoconstriction and tissue remodeling. Here, we studied LT crosstalk between myeloid cells and pulmonary epithelial cells. Monocytic cells (Mono Mac 6 cell line, prim...

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Bibliografische gegevens
Gepubliceerd in:J Lipid Res
Hoofdauteurs: Lukic, Ana, Ji, Jie, Idborg, Helena, Samuelsson, Bengt, Palmberg, Lena, Gabrielsson, Susanne, Rådmark, Olof
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003151/
https://ncbi.nlm.nih.gov/pubmed/27436590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066910
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