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Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A(4) production
Regulation of 5-lipoxygenase (5LO) activity is a key determinant for the biosynthesis of proinflammatory leukotrienes. Coactosin-like protein (CLP) is an F-actin-binding protein that can also bind 5LO. Here, we report that CLP can up-regulate and modulate 5LO activity [formation of 5(S)-hydroperoxy-...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1559768/ https://ncbi.nlm.nih.gov/pubmed/16924104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605150103 |
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