5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases
5-lipoxygenase (5-LO) catalyzes the initial steps in the formation of leukotrienes, a group of inflammatory mediators derived from arachidonic acid (AA). Here we describe that activation of p38 mitogen-activated protein kinase in human polymorphonuclear leukocytes and in Mono Mac 6 cells leads to ac...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25816/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10779545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050588997 |
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