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Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C(4) to leukotriene D(4)

Leukotrienes (LTs) play major roles in lung immune responses, and LTD(4) is the most potent agonist for cysteinyl LT1, leading to bronchoconstriction and tissue remodeling. Here, we studied LT crosstalk between myeloid cells and pulmonary epithelial cells. Monocytic cells (Mono Mac 6 cell line, prim...

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Podrobná bibliografie
Vydáno v:J Lipid Res
Hlavní autoři: Lukic, Ana, Ji, Jie, Idborg, Helena, Samuelsson, Bengt, Palmberg, Lena, Gabrielsson, Susanne, Rådmark, Olof
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003151/
https://ncbi.nlm.nih.gov/pubmed/27436590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066910
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