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5-Lipoxygenase: mechanisms of regulation

5-Lipoxygenase (5-LO) catalyzes two steps in biosynthesis of leukotrienes (LTs), a group of lipid mediators of inflammation derived from arachidonic acid (AA). LT antagonists are used in treatment of asthma; more recently a potential role also in atherosclerosis has raised considerable interest. Fur...

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Bibliografiska uppgifter
Huvudupphovsmän: Rådmark, Olof, Samuelsson, Bengt
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674731/
https://ncbi.nlm.nih.gov/pubmed/18987389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800062-JLR200
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