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5-Lipoxygenase: mechanisms of regulation
5-Lipoxygenase (5-LO) catalyzes two steps in biosynthesis of leukotrienes (LTs), a group of lipid mediators of inflammation derived from arachidonic acid (AA). LT antagonists are used in treatment of asthma; more recently a potential role also in atherosclerosis has raised considerable interest. Fur...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674731/ https://ncbi.nlm.nih.gov/pubmed/18987389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800062-JLR200 |
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